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Evid Based Nurs 8:42 doi:10.1136/ebn.8.2.42
  • Treatment

Review: β agonist delivery by metered dose inhaler with a valved holding chamber (compared with a nebuliser) reduces admissions in preschool children and infants with acute asthma or wheezing

β agonist delivery by metered dose inhaler (MDI) with a valved holding chamber (VHC) v delivery by nebuliser in children <5 years of age with acute exacerbation of asthma or wheezing*

Outcome Number of trials (n) MDI + VHC Nebuliser RRR (95% CI) NNT (CI)
*Abbreviations defined in glossary; RRR, NNT, and CI calculated from control event rate and odds ratio and CI reported in article.
Hospital admission 6 (491) 11% 22% 52% (23 to 71) 9 (7 to 20)

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