rss
Evid Based Nurs 8:42 doi:10.1136/ebn.8.2.42
  • Treatment

Review: β agonist delivery by metered dose inhaler with a valved holding chamber (compared with a nebuliser) reduces admissions in preschool children and infants with acute asthma or wheezing


 
 Q What is the relative efficacy of β agonists delivered by metered dose inhaler (MDI) with a valved holding chamber (VHC) or by nebuliser in infants and preschool children with acute exacerbations of wheezing or asthma?

METHODS

GraphicData sources:

Medline (1966–2003), EMBASE/Excerpta Medica (1980–2003), Cochrane Controlled Trials Register; and reference lists of included studies, reviews, and texts.

GraphicStudy selection and assessment:

randomised controlled trials (RCTs) in any language that compared β agonist delivery by MDI + VHC with delivery by nebuliser in infants and children <5 years of age who presented to the emergency department (ED) or equivalent setting with acute exacerbation of wheezing or asthma. Exclusion criterion: studies of admitted patients. Methodological quality of individual studies was assessed using the 5 point Jadad scale (adequacy of randomisation, blinding, and handling of withdrawals and dropouts).

GraphicOutcomes:

primary outcome was admission to hospital; secondary outcomes included final clinical score.

MAIN RESULTS

6 RCTs (491 children, 1–60 mo) met the selection …

No Related Web Pages

Free Sample

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of EBN.
View free sample issue >>

EBN Journal Chat

The EBN Journal Chat offers readers the opportunity to participate in discussion about research articles and commentaries from Evidence Based Nursing (EBN).

How to participate >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Navigate This Article