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Evid Based Nurs 8:41 doi:10.1136/ebn.8.2.41
  • Treatment

Dexamethasone reduced the incidence of children with mild croup who returned for medical care


 
 Q Does dexamethasone reduce the incidence of children with mild croup who return for medical care more than placebo?

METHODS

GraphicDesign:

randomised placebo controlled trial.

GraphicAllocation:

unclear allocation concealment.

GraphicBlinding:

blinded (patients and data analysts).

GraphicFollow up period:

7 days after treatment.

GraphicSetting:

4 paediatric emergency departments (EDs) in Canada.

GraphicPatients:

720 children (mean age 35 mo, 61% boys) with mild croup (onset of a seal like, barking cough in the previous 72 h and ⩽2 out of 17 points on a validated croup scoring system). Exclusion criteria included other respiratory disorders, severe systemic disease, immune dysfunction, corticosteroids within the previous 2 weeks, epinephrine for respiratory distress, and previous ED visit for this croup episode.

GraphicIntervention:

single oral dose of dexamethasone suspension (12.5 ml DM phosphate injection plus 50 ml of cherry flavoured syrup, 0.6 mg/kg of body weight (maximum 20 mg) (n = 359) or placebo (10 ml of distilled water plus …

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