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Evid Based Nurs 8:25 doi:10.1136/ebn.8.1.25
  • Prognosis

Having a stroke increased the risk of developing dementia in older people

Association between baseline stroke and incidence of dementia in older people*

Variable adjusted for Number of patients with dementia (N) Hazard ratio (95% CI)
*N  =  total number of cases plus controls with information available on the status of each vascular risk factor; ABI  =  atherothrombotic brain infarct; CE  =  cardioembolic. CI defined in glossary.
†Adjusted for age, sex, and education in addition to listed variable.
None: crude risk 158 (1272) 2.2 (1.5 to 3.1)
Age, sex, and education 153 (1239) 2.0 (1.4 to 2.9)
Apolipoprotein E ε4 genotype status† 92 (801) 2.8 (1.7 to 4.4)
Stroke type (hemisphere, ABI/CE)† 153 (1239) 2.0 (1.4 to 2.9)
Second stroke† 153 (1239) 2.0 (1.4 to 2.9)
Second stroke and stroke risk factors (hypertension, diabetes, atrial fibrillation, current smoking)† 114 (844) 2.4 (1.6 to 3.7)

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