|Outcomes at 7.6–35 days||Number of trials (n)||Weighted event rates||RRR (95% CI)||NNT (CI)|
|NPPV plus usual care||Usual care alone|
|*Treatment failure = a composite of all cause mortality, endotracheal intubation, and intolerance to the allocated treatment. Other abbreviations defined in glossary; weighted event rates, RRR, and CI calculated from data in article using a fixed effects model.|
|Treatment failure||8 (541)||19.7%||41.7%||52% (37 to 63)||5 (4 to 7)|
|All cause mortality||10 (622)||10.8%||20.8%||48% (24 to 65)||10 (7 to 25)|
|Endotracheal intubation||14 (758)||16.5%||40.5%||59% (47 to 67)||5 (4 to 6)|
Review: adding non-invasive positive pressure ventilation to usual care reduces treatment failure in respiratory failure
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