|Outcomes||Paracetamol v placebo||NSAIDs v paracetamol|
|Number of comparisons (n)||Pooled effect size (95% CI)||Number of comparisons (n)||Pooled effect size (CI)|
|*NA = not available. WOMAC = Western Ontario and McMaster University. CI defined in glossary.|
|†Significant result favouring paracetamol over placebo.|
|‡Significant result favouring NSAIDs over paracetamol.|
|Pain||2 (394)||0.21 (0.02 to 0.41)†||11 (1641)||0.20 (0.10 to 0.30)‡|
|WOMAC OA score||2 (394)||0.14 (−0.06 to 0.34)||4 (NA)||0.30 (0.17 to 0.44)‡|
|Function||Not assessed||Not assessed||6 (NA)||0.22 (0.08 to 0.34)‡|
|Stiffness||Not assessed||Not assessed||5 (NA)||0.35 (0.19 to 0.50)‡|
Review: paracetamol reduces pain in osteoarthritis but is less effective than NSAIDs
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