Article Text

Download PDFPDF
Review: long term use of common medications for asthma reduces exacerbations in adults

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

OpenUrlCrossRefPubMedWeb of Science

Q In adults with asthma, does long term use of common pharmacological antiasthmatic agents reduce rates of exacerbations?

METHODS

Embedded ImageData sources:

Medline, EMBASE/Excerpta Medica, and the Cochrane databases (all from 1980 to April 2004); bibliographies of relevant articles; and experts.

Embedded ImageStudy selection and assessment:

randomised controlled trials (RCTs) (published in English) that lasted ⩾3 months, evaluated common pharmacological treatments for adults (>19 y of age) with asthma, and reported relevant outcomes. Study quality was assessed using the Jadad scale.

Embedded ImageOutcomes:

exacerbation rates and forced expiratory volume in 1 second (FEV1).

MAIN RESULTS

4 categories of pharmacological medications were evaluated. Meta-analyses were done using a random effects model when significant data heterogeneity was detected. (1) Inhaled corticosteroids (ICSs) …

View Full Text

Footnotes

  • For correspondence: Dr D D Sin, James Hogg iCAPTURE Center for Cardiovascular and Pulmonary Research, University of British Columbia, Vancouver, Canada. dsinmrl.ubc.ca

  • Source of funding: no external funding.