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Evid Based Nurs 8:13 doi:10.1136/ebn.8.1.13
  • Treatment

Review: all forms of nicotine replacement therapy are effective for smoking cessation

Nicotine replacement therapy (NRT) v placebo or no treatment (control) for smoking cessation at 6–12 months*

Comparison Number of trials (n) Weighted event rates RBI (95% CI) NNT (CI)
*Abbreviations defined in glossary; weighted event rates, RBI, NNT, and CI calculated from data in article using a fixed effects model.
Any NRT v control 103 (38 602) 16% v 10% 58% (50 to 67) 17 (15 to 17)
Gum v control 52 (17 819) 18% v 12% 48% (38 to 59) 17 (15 to 20)
Patch v control 37 (16 228) 14% v 8.1% 71% (55 to 88) 17 (15 to 20)
Intranasal spray v control 4 (887) 24% v 12% 102% (49 to 173) 9 (6 to 15)
Inhaler v control 4 (976) 17% v 9.1% 90% (36 to 167) 13 (9 to 25)
Tablet v control 4 (2739) 16% v 9% 87% (52 to 223) 13 (10 to 20)

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