|Outcomes||Dosage||Number of studies (n)||Weighted mean difference (95% CI)|
|*CI defined in glossary. Mean differences based on a fixed effects model.|
|†Not statistically significant.|
|Subjective assessment of congestion at 2 hours||Single||4 (195)||−0.13 (−0.19 to −0.07)|
|Subjective assessment of congestion (5 d mean)||Repeated||1 (31)||−0.07 (−0.21 to 0.07)†|
|Standardised mean difference (CI)|
|Objective assessment of congestion (nasal airways resistance) at 2 hours||Single||4 (177)||−0.56 (−0.86 to −0.25)|
Review: a single dose of nasal decongestant reduces congestion in the short term in adults with the common cold; insufficient evidence exists on the effectiveness of repeated doses
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