Prognostic factors for mortality in community dwelling patients with newly diagnosed Alzheimer’s disease*
| Prognostic factor | Median years of survival† | Hazard ratio (95% CI)‡ |
|---|---|---|
| *MMSE = Mini Mental State Examination; DRS = Dementia Rating Scale; other abbreviations defined in glossary. | ||
| †Time until death when 50% of patients died. | ||
| ‡Independent prognostic factors based on proportional hazards model adjusted for age at diagnosis, sex, and ethnicity. | ||
| MMSE score ⩽17 | 3.6 | 2.58 (1.88 to 3.53) |
| DRS score 5.5–17 | 3.2 | 2.15 (1.62 to 2.84) |
| Frontal lobe release signs | 4.6 | 1.26 (1.03 to 1.54) |
| Gait disturbance | 3.5 | 1.50 (1.20 to 1.87) |
| History of falls | 4.3 | 1.30 (1.05 to 1.60) |
| Ischaemic heart disease | 4.1 | 1.30 (1.05 to 1.61) |
| Congestive heart failure | 3.0 | 1.48 (1.10 to 1.99) |
| Diabetes | 3.8 | 1.87 (1.34 to 2.61) |
