|Prognostic factor||Median years of survival†||Hazard ratio (95% CI)‡|
|*MMSE = Mini Mental State Examination; DRS = Dementia Rating Scale; other abbreviations defined in glossary.|
|†Time until death when 50% of patients died.|
|‡Independent prognostic factors based on proportional hazards model adjusted for age at diagnosis, sex, and ethnicity.|
|MMSE score ⩽17||3.6||2.58 (1.88 to 3.53)|
|DRS score 5.5–17||3.2||2.15 (1.62 to 2.84)|
|Frontal lobe release signs||4.6||1.26 (1.03 to 1.54)|
|Gait disturbance||3.5||1.50 (1.20 to 1.87)|
|History of falls||4.3||1.30 (1.05 to 1.60)|
|Ischaemic heart disease||4.1||1.30 (1.05 to 1.61)|
|Congestive heart failure||3.0||1.48 (1.10 to 1.99)|
|Diabetes||3.8||1.87 (1.34 to 2.61)|
Severity of cognitive impairment at initial diagnosis of Alzheimer’s disease was the strongest predictor of survival
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