Review: probiotics reduced diarrhoea at 3 days in children and adults with proven or presumed infectious diarrhoea
Q Are probiotics effective for proven or presumed infectious diarrhoea in children and adults?
Cochrane Infectious Diseases Group trials register (December 2002), Cochrane Controlled Trials Register (Issue 4, 2002), Medline (1966–2002), and EMBASE/Excerpta Medica (1988–2002); existing reviews; reference lists of retrieved trials; experts and relevant organisations; and 5 manufacturers of probiotics.
Study selection and assessment:
published and unpublished randomised controlled trials (RCTs) in any language that compared specific probiotics with placebo or no probiotic in adults and children with acute diarrhoea (<14 d) that was proven or presumed to be caused by an infectious agent. 2 independent reviewers assessed the methodological quality of individual studies in terms of generation of allocation sequence, allocation concealment, blinding, and …