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Evid Based Nurs 7:107 doi:10.1136/ebn.7.4.107
  • Treatment

Review: probiotics reduced diarrhoea at 3 days in children and adults with proven or presumed infectious diarrhoea


 
 Q Are probiotics effective for proven or presumed infectious diarrhoea in children and adults?

METHODS

GraphicData sources:

Cochrane Infectious Diseases Group trials register (December 2002), Cochrane Controlled Trials Register (Issue 4, 2002), Medline (1966–2002), and EMBASE/Excerpta Medica (1988–2002); existing reviews; reference lists of retrieved trials; experts and relevant organisations; and 5 manufacturers of probiotics.

GraphicStudy selection and assessment:

published and unpublished randomised controlled trials (RCTs) in any language that compared specific probiotics with placebo or no probiotic in adults and children with acute diarrhoea (<14 d) that was proven or presumed to be caused by an infectious agent. 2 independent reviewers assessed the methodological quality of individual studies in terms of generation of allocation sequence, allocation concealment, blinding, and …

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