|Outcomes at 5 years||Simvastatin||Placebo||RRR (95% CI)||NNT (CI)|
|*Abbreviations defined in glossary; NNT and CI calculated from control event rate and rate ratio reported in article.|
|†Non-fatal myocardial infarction or coronary death, stroke, or revascularisation procedure.|
|≥1 major vascular event†||20%||25%||24% (19 to 28)||17 (15 to 21)|
|≥1 stroke||4.3%||5.7%||25% (15 to 34)||71 (52 to 117)|
|≥1 ischaemic stroke||2.8%||4.0%||30% (19 to 40)||84 (63 to 133)|
Cholesterol lowering with simvastatin reduced stroke in patients with, or at risk of, vascular disease
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