Evid Based Nurs 7:74 doi:10.1136/ebn.7.3.74
  • Treatment

Review: antibiotics are moderately effective for acute otitis media in children

Antibiotics v placebo for acute otitis media in children*

Outcomes at ⩽56 days Number of trials (patients) Weighted event rates RRI (95% CI) NNH
Antibiotics Placebo
*Abbreviations defined in glossary; weighted event rates, RRI, RRR, NNH, NNT, and CI calculated from data in article using a fixed effects model.
Pain at ⩽24 hours 3 (717) 38% 37% 2% (−15 to 22) Not significant
Pain at 2–7 days 8 (2287) 15% 22% 30% (19 to 40) 15 (10 to 25)
Recurrence 5 (1669) 22% 22% 0% (−19 to 17) Not significant
Vomiting, diarrhoea, or rash 4 (938) 17% 11% 60 (19 to 116) 17 (10 to 50)

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