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Evid Based Nurs 7:41 doi:10.1136/ebn.7.2.41
  • Treatment

Higher oxygen saturation targets did not improve growth and neurodevelopment in extremely preterm infants

Higher oxygen saturation targets (95–98%) v standard saturation targets (91–94%) for extremely premature infants*

Outcomes at 12 months corrected age Higher targets Standard targets Mean difference (95% CI)
*PA  =  postmenstrual age; other abbreviations defined in glossary. RRI, NNH, and CI calculated from data in article.
Weight (kg) 9.25 9.10 0.15 (−0.2 to 0.5)
Length (cm) 74.1 74.0 0.1 (−0.8 to 1.0)
Head circumference (cm) 46.3 46.3 0.0 (−0.4 to 0.4)
RRR (CI) NNT
Weight <10th percentile 33% 37% 11.4% (−34 to 19) Not significant
Major developmental abnormality 23% 24% 3.7% (−34 to 41) Not significant
RRI (CI) NNH (CI)
Dependence on supplemental oxygen at 36 wks PA 64% 46% 40% (16 to 70) 6 (4 to 13)

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