Evid Based Nurs 7:16 doi:10.1136/ebn.7.1.16
  • Treatment

Oestrogen plus progestogen increased risk of breast cancer in postmenopausal women

Oestrogen plus progestogen (Oest + Prog) v placebo for postmenopausal women*

Outcomes at mean 5.6 years Oest + Prog Placebo Hazard ratio (95% CI)
*CI defined in glossary.
†Not significant.
Cases of breast cancer (all) 245 185 1.24 (1.02 to 1.50)
Cases of invasive breast cancer 199 150 1.24 (1.01 to 1.54)
Cases of in situ breast cancer 47 37 1.18 (0.77 to 1.82)†

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