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Evid Based Nurs 7:12 doi:10.1136/ebn.7.1.12
  • Treatment

Review: metered dose inhalers with a holding chamber do not differ from nebulisers for hospital admission rates in asthma

Inhalation of β2 agonists from a metered dose inhaler with a holding chamber v inhalation from a nebuliser in acute asthma*

Weighted event rates
Outcomes Patients Number of RCTs (n) Chamber Nebuliser RRR (95% CI) NNT
*Abbreviations defined in glossary; RRR, NNT, and CI calculated from data in article.
Admission to hospital Adults 6 (352) 13% 15% 12% (−38 to 46) Not significant
Children 5 (353) 12% 16% 35% (−6 to 60) Not significant

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