Review: metered dose inhalers with a holding chamber do not differ from nebulisers for hospital admission rates in asthma
Q In patients with acute asthma, is inhalation of β2 agonists from a metered dose inhaler (MDI) with a holding chamber more effective than inhalation from a nebuliser for reducing hospital admission rates or duration of inpatient stay?
Cochrane Airways Group Trials Register (November 2002), the Cochrane Library (2002, Issue 3), bibliographies of relevant articles, and individual researchers in the field.
Study selection and assessment:
randomised controlled trials (RCTs) published in any language that compared any β2 agonist given by an MDI with any holding chamber with the same β2 agonist given by any nebuliser in adults or children with acute asthma presenting for medical assistance in the hospital emergency department.
admission to hospital and duration of inpatient stay.
22 RCTs (444 adults …