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Evid Based Nurs 6:113 doi:10.1136/ebn.6.4.113
  • Treatment

Oral vitamin D3 supplementation reduced fractures in community dwelling elderly people

(2003) BMJ 326, 469; Trivedi DP, Doll R, Khaw KT.. Effect of four monthly oral vitamin D. 3. (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. . ;. :. –72.


 
 QUESTION: Does oral vitamin D3 (cholecalciferol) supplementation reduce the incidence of fractures in community dwelling elderly people 65–85 years of age?

Design

Randomised (unclear allocation concealment), blinded (participants and clinicians), placebo controlled trial with 5 years of follow up.

Setting

Community based study with participants recruited from the British Doctors Study register and a general practice register in Suffolk, UK.

Participants

2686 elderly people 65–85 years of age (mean age 75 y, 76% men) who were living in the general community. Exclusion criteria included current use of vitamin D3 supplements and contraindications to vitamin D3 supplementation such as a history of renal stones, sarcoidosis, or malignancy.

Intervention

Participants, stratified by age and sex, were allocated to …

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