Treatment of hypertension reduces risk of complications in type 2 diabetes
QUESTION: In patients with type 2 diabetes mellitus, what are the optimal blood pressure (BP) goals and pharmaceutical agents to reduce risk of complications?
The Cochrane Collaboration Diabetes Group report was used to identify studies published before 1997. Recent studies were identified by searching Medline in May 2000 and again in April 2002. Bibliographies of meta-analyses and review articles were scrutinised, and experts in the field were contacted for further studies.
Studies were selected if they were randomised controlled trials (RCTs) that compared an antihypertensive drug with placebo, the effects of different target BP levels, or the effects of different classes of drugs, and measured relevant clinical end points in patients with type 2 diabetes mellitus.
Data were extracted on sample size, interventions, …