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Evid Based Nurs 6:76 doi:10.1136/ebn.6.3.76
  • Treatment

Review: regular inhaled long acting β2 agonists are associated with better outcomes than short acting β2 agonists in adults and children with chronic asthma

Regular long acting v short acting inhaled β2 agonists in adults and children with chronic asthma

Outcomes at 2–24 weeks (number of studies) Weighted mean difference (95% CI)
Morning peak expiratory flow (l/min) (n=8) 33 (25 to 41)
Evening peak expiratory flow (l/min) (n=8) 26 (18 to 33)
Forced expiratory volume in 1 second (l) (n=8) 0.23 (0.14 to 0.31)
Daytime asthma symptom score (n=3) −0.15 (−0.23 to −0.06)
Night time asthma symptom score (n=3) −0.21 (−0.31 to −0.10)
Percentage of days without symptoms (n=2) 10 (2 to 19)
Percentage of nights without symptoms (n=3) 12 (8 to 16)
Daytime use of rescue bronchodilators (puffs/24 h) (n=4) −0.33 (−0.50 to −0.16)
Night time use of rescue bronchodilators (puffs/24 h) (n=4) −0.31 (−0.43 to −0.19)

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