Review: regular inhaled long acting β2 agonists are associated with better outcomes than short acting β2 agonists in adults and children with chronic asthma
QUESTION: What is the effectiveness of regular inhaled long acting β2 agonists compared with inhaled short acting β2 agonists in adults and children with chronic asthma?
Studies were identified using the Cochrane Airways Review Group register, which is derived from searching Medline, CINAHL, and EMBASE/Excerpta Medica. In addition, bibliographies of relevant studies were scanned, key respiratory care journals were hand searched, and experts were contacted.
Randomised controlled trials of ≥2 weeks duration were selected if they compared a regular inhaled long acting β2 agonist with a regular inhaled short acting β2 agonist of equivalent (as far as possible) bronchodilator effectiveness in adults or children with chronic asthma (ie, those with a diagnosis of ≥6 mo). Studies including participants with other pulmonary …