Parallel arm studies of anticholinergic drugs v placebo for overactive bladder syndrome in adults at 12 days to 12 weeks*
| Weighted event rates | ||||
|---|---|---|---|---|
| Outcomes | Anticholinergic drugs | Placebo | RBI (95% CI) | NNT (CI) |
| Self reported cure or improvement (8 studies) | 63% | 45% | 41% (29 to 54) | 6 (5 to 8) |
| RRI (CI) | NNH (CI) | |||
|---|---|---|---|---|
| Dry mouth (20 studies) | 36% | 15% | 138 (70 to 232) | 5 (4 to 7) |
| Outcomes | Weighted mean difference (CI) | |||
|---|---|---|---|---|
| *Abbreviations defined in glossary; RBI, RRI, NNT, NNH, and CI calculated from data in article. | ||||
| Number of leakage episodes in 24 hours (9 studies) | −0.56 (–0.73 to –0.39) | |||
| Number of micturitions in 24 hours (8 studies) | −0.59 (–0.83 to –0.36) | |||
| Maximum cystometric volume (ml) (12 studies) | 54.3 (43.0 to 65.7) | |||
| Volume at first contraction (ml) (9 studies) | 52.3 (37.5 to 67.1) | |||
| Residual volume (ml) (11 studies) | 4.1 (0.73 to 7.4) | |||
