Doppler echocardiography was not accurate for diagnosing asymptomatic thrombosis associated with an umbilical venous catheter in infants
QUESTION: What is the accuracy of Doppler echocardiography for diagnosing asymptomatic thrombosis associated with an indwelling umbilical venous catheter (UVC) in infants?
Blinded comparison of Doppler echocardiography with contrast venography.
A neonatal intensive care unit (NICU) at a university based hospital in Hamilton, Ontario, Canada.
47 infants (mean gestational age 32.2 wks, mean birth weight 1962 g, 51% boys) who had in situ UVCs for ≥48 hours and the catheter was scheduled for elective removal. All catheters had single lumens and were made of polyvinyl chloride; heparin was not added to intravenous solutions and no blood products were given through the UVC. Exclusion criteria were symptoms and signs of catheter associated thrombosis or catheter malfunction; known anatomic defects of the heart and great vessels; failure to position the tip of the catheter just above the diaphragm, in either …