Doppler echocardiography was not accurate for diagnosing asymptomatic thrombosis associated with an umbilical venous catheter in infants
QUESTION: What is the accuracy of Doppler echocardiography for diagnosing asymptomatic thrombosis associated with an indwelling umbilical venous catheter (UVC) in infants?
Design
Blinded comparison of Doppler echocardiography with contrast venography.
Setting
A neonatal intensive care unit (NICU) at a university based hospital in Hamilton, Ontario, Canada.
Patients
47 infants (mean gestational age 32.2 wks, mean birth weight 1962 g, 51% boys) who had in situ UVCs for ≥48 hours and the catheter was scheduled for elective removal. All catheters had single lumens and were made of polyvinyl chloride; heparin was not added to intravenous solutions and no blood products were given through the UVC. Exclusion criteria were symptoms and signs of catheter associated thrombosis or catheter malfunction; known anatomic defects of the heart and great vessels; failure to position the tip of the catheter just above the diaphragm, in either …








