Evid Based Nurs 6:18 doi:10.1136/ebn.6.1.18
  • Treatment

Review: chlorhexidine gluconate is more effective than povidone-iodine for preventing vascular catheter related bloodstream infection

Chlorhexidine gluconate (Chlor) v povidone-iodine (PI) for vascular catheter site care*

Weighted event rates
Outcomes Chlor PI RRR (95% CI) NNT (CI)
*Abbreviations defined in glossary. Chlorhexidine event rates calculated from control event rate and absolute risk reduction reported in article; RRR (CI) and NNT (CI) calculated from control event rate and relative risk (CI) reported in article.
Catheter related blood stream infection (7 trials, n=3899) 1.0% 2.1% 51% (12 to 72) 93 (66 to 393)
Patients with positive cultures (8 trials, n=4001) 6.4% 13.5% 51% (29 to 69) 15 (11 to 26)

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