Evid Based Nurs 5:112 doi:10.1136/ebn.5.4.112
  • Treatment

Losartan reduced stroke and new onset diabetes more than atenolol in essential hypertension with signs of left ventricular hypertrophy

Losartan based treatment v atenolol based treatment for essential hypertension with signs of left ventricular hypertrophy*

Outcomes Losartan Atenolol RRR (95% CI) NNT (CI)
*Abbreviations defined in glossary; RRR, NNT, and CI calculated from data in article.
†Cardiovascular mortality, stroke, and myocardial infarction.
Composite end point† 11% 13% 12% (2 to 22) 64 (36 to 418)
Stroke 5% 7% 24% (11 to 36) 61 (42 to 140)
New onset diabetes 6% 8% 24% (12 to 36) 52 (35 to 108)

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