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Evid Based Nurs 5:100-104 doi:10.1136/ebn.5.4.100

Evaluation of studies of health economics

Table 4

Summary of an economic analysis on central line catheters and catheter related blood stream infection (CRBSI)

Feature Study by Veenstra et al, 1999
Overall study design Cost effectiveness analysis using a decision analytic model
Perspective of analysis Healthcare payer
Alternatives compared Standard or antiseptic impregnated multilumen central venous catheters
Effect measures Incidence of CRBSI, death
Source of effectiveness data Randomised controlled trials, meta-analysis, case control studies
Source of quality of life (utility) weights N/A
Estimates of resource use University of Washington Medical Center and the literature
Source of cost data Direct medical costs – University of Washington Medical Center and the literature
Discounting N/A
Addressing uncertainty Multivariate sensitivity analyses with varying estimates of direct medical costs, incidence of CRBSI, and death attributable to CRBSI or hypersensitivity reactionUnivariate sensitivity analyses for incremental costs: cost of CRBSI, relative risk of CRBSI, incidence of CRBSI, and additional catheter cost Univariate sensitivity analyses for incremental incidence of death: relative risk of CRBSI, incidence of CRBSI, probability of death attributable to CRBSI, and probability of hypersensitivity

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