|Feature||Study by Veenstra et al, 1999|
|Overall study design||Cost effectiveness analysis using a decision analytic model|
|Perspective of analysis||Healthcare payer|
|Alternatives compared||Standard or antiseptic impregnated multilumen central venous catheters|
|Effect measures||Incidence of CRBSI, death|
|Source of effectiveness data||Randomised controlled trials, meta-analysis, case control studies|
|Source of quality of life (utility) weights||N/A|
|Estimates of resource use||University of Washington Medical Center and the literature|
|Source of cost data||Direct medical costs – University of Washington Medical Center and the literature|
|Addressing uncertainty||Multivariate sensitivity analyses with varying estimates of direct medical costs, incidence of CRBSI, and death attributable to CRBSI or hypersensitivity reactionUnivariate sensitivity analyses for incremental costs: cost of CRBSI, relative risk of CRBSI, incidence of CRBSI, and additional catheter cost Univariate sensitivity analyses for incremental incidence of death: relative risk of CRBSI, incidence of CRBSI, probability of death attributable to CRBSI, and probability of hypersensitivity|
Evaluation of studies of health economics
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