You are here

Article Text

Article menu
Download PDFPDF
Causation
Review: breast cancer is associated with a family history of the disease in first degree relatives

https://doi.org/10.1136/ebn.5.3.89

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Collaborative Group on Hormonal Factors in Breast Cancer. Familial breast cancer: collaborative reanalysis of individual data from 52 epidemiological studies including 58 209 women with breast cancer and 101 986 women without the disease.Lancet2001 Oct 27;358:1389–99OpenUrlCrossRefPubMedWeb of Science

    QUESTION: In women with a family history of breast cancer, how does the pattern of breast cancer in first degree relatives affect the risk of developing the disease?

    Data sources

    Studies were identified by searching computerised literature databases, reviewing bibliographies of review articles, and contacting experts in the field.

    Study selection

    Studies were selected if they were cohort or nested case control studies, included ≥100 women with incident invasive breast cancer, and information about reproductive or hormonal factors was sought on each woman.

    Data extraction

    Principal investigators of the included studies were contacted for data on each woman regarding whether any of her first degree female relatives (mother, sisters, or daughters) had been diagnosed with breast cancer and, if so, their age when the diagnosis was made. Data were also collected on the numbers of …

    View Full Text