Intravenous fluid replacement minimised dehydration during sodium picosulphate bowel preparation for colonic surgery
QUESTION: In patients receiving sodium picosulphate (Picolax®) bowel preparation before colonic surgery, does intravenous fluid replacement minimise dehydration?
Randomised (unclear allocation concealment), unblinded, controlled trial with follow up to 1 hour before surgery or immediately before premedication.
Colorectal Unit, Derriford Hospital, Plymouth, UK.
41 patients (median age 69 y, 63% men) who were receiving bowel preparation for colonic surgery. Follow up was 100%.
19 patients were allocated to receive a calculated volume (mean 2 l) of intravenous normal saline (treatment group), and 22 were allocated to receive no intravenous fluid (control group) during bowel preparation. Intravenous fluid administration (hourly infusion rate 4 ml/kg for the first 10 kg, 2 ml/kg for the second 10 kg, and 1 ml/kg …