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A semidemand feeding protocol reduced time to full oral feeding in healthy preterm infants

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QUESTION: In healthy preterm infants, is a semidemand feeding protocol more effective than the standard practice of scheduled feedings for reducing the time to attain full oral feeding and maintaining a satisfactory weight gain?

Design

Randomised (unclear allocation concealment), unblinded controlled trial with {follow up to attainment of full oral feeding}*.

Setting

2 neonatal intensive care units in Cincinnati, Ohio, USA.

Participants

89 preterm infants who were 32 to ≤34 weeks postconceptional age and appropriate for gestational age. Infants with congenital anomalies, gastrointestinal conditions, neurological diagnoses, or grade III/IV intracranial haemorrhage were excluded. 81 infants (91%) completed the study (mean postconceptional age at study entry 32 wks, 53% boys).

Intervention

44 infants were allocated to a semidemand feeding protocol. 10 minutes of non-nutritive sucking (NNS) were provided every 3 hours, followed up by an assessment of behavioural state (modified Anderson Behavioral State scale). If the infant was judged to be in a state of …

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Footnotes

  • Source of funding: National Institutes of Health.

  • For correspondence: Dr G C McCain, Children's Hospital Medical Center, Cincinnati, OH, USA. gmc2{at}po.cwru.edu