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Evid Based Nurs 5:73 doi:10.1136/ebn.5.3.73
  • Treatment

Chlorhexidine reduced catheter tip colonisation more than 10% povidone-iodine in critically ill neonates

Chlorhexidine v 10% povidone-iodine (PI) for reducing infection rates in neonates†

Outcomes (all catheters) at time of assessment Chlorhexidine 10% PI RRR (95% CI) NNT (CI)
Catheter tip colonisation 15% 24% 40% (10 to 50) 11 (9 to 42)
RRI (CI) NNH (CI)
†BSI = bloodstream infection; CRBSI = catheter related bloodstream infection. Other abbreviations defined in glossary; RRR, RRI, NNT, NNH, and CI calculated from data in article.
CRBSI 3.8% 3.2% 20% (-50 to 170) Not significant
BSI without a source 15% 14% 10% (-20 to 50) Not significant

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