|Interventions||Number of RCTs||Number of patients||Overall effect: number of studies showing improvement or no difference|
|*RCTs = randomised controlled trials; GET = graded exercise therapy; CBT = cognitive behavioural therapy. Intervention duration ranged from 2 weeks to 1 year (mean 16 wks); follow up ranged from 2 weeks to 5 years.|
|Behavioural||8||883||6 improvement; 2 no difference|
|CBT||5||533||3 improvement; 2 no difference|
|Immunological||9||440||4 improvement; 5 no difference|
|Pharmacological||12||896||2 improvement; 10 no difference|
|Supplements||5||174||2 improvement; 3 no difference|
|Complementary or alternative||2||84||1 improvement; 1 no difference|
Review: behavioural interventions show the most promise for chronic fatigue syndrome
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