Fracture risk was increased after stroke with a marked increase immediately after stroke
QUESTIONS: Does risk of fracture increase after stroke? What is the time course of any increase in fracture risk?
Inception cohort followed up for ≤10 years (mean 2.5 y).
273 288 patients (mean age 74 y, 50% men) admitted to hospital with a first ever stroke identified using the National Swedish Register.
Assessment of prognostic factors
All hospital records were examined to identify people who were admitted to hospital for stroke during a 10 year period. Age, sex, and duration of hospital stay were recorded.
Main outcome measure
Subsequent admission to hospital for fracture.
24 666 people (9%) had a fracture subsequent to stroke, of which 14 263 (58%) were hip fractures. The incidence of all fractures and hip fractures in patients with stroke was compared with the general population. For any fracture requiring admission to hospital, the relative risk (RR) was greatest in the younger age groups (RR 2.38 to 4.69). RR declined with age but was …