Evid Based Nurs 4:73 doi:10.1136/ebn.4.3.73
  • Treatment

Amethocaine gel reduced pain during venipuncture in newborn infants

 QUESTION: Does topical amethocaine gel reduce pain during venipuncture in newborn infants?


Randomised (allocation concealed), blinded (patients, clinicians, outcome assessors), placebo controlled trial with follow up immediately after the procedure.


Postnatal wards and the neonatal intensive care unit at the Nottingham City Hospital, Nottingham, UK.


40 newborn infants (median age 7 d, median gestational age 33 wks) who required venipuncture as part of their routine care. Infants who were unwell, ventilated, or sedated were excluded. Follow up was 98%.


20 infants were allocated to 1.5 g of 4% amethocaine gel and 20 were allocated to 1.5 g of placebo gel. The gel was applied to the dorsum of the hand or foot and covered with an occlusive dressing. After …

Free Sample

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of EBN.
View free sample issue >>

EBN Journal Chat

The EBN Journal Chat offers readers the opportunity to participate in discussion about research articles and commentaries from Evidence Based Nursing (EBN).

How to participate >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Navigate This Article