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An antenatal index predicted postpartum depression with high sensitivity and moderate specificity

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QUESTION: Are there demographic, perinatal, and psychosocial risk factors that can be used to develop a predictive index for postpartum depression?

Design

2 cohort studies: 1 to identify the predictors (derivation cohort) and 1 to validate their predictive ability (validation cohort).

Setting

Antenatal care clinic and delivery ward in a university hospital in Denmark.

Patients

6790 Danish speaking women (mean age 30 y) who attended an antenatal programme for a second trimester examination and who gave birth between 1 January 1994 and 31 December 1995 formed the derivation cohort. 528 women enrolled in the antenatal programme in the 4 months immediately before and after the study period formed the validation cohort.

Description of prediction guide

2 predictive indices were considered: 1 index involving only antenatal risk factors, and the other involving both …

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Footnotes

  • Sources of funding: Ministry of Health; Eli Lilly (Denmark).

  • For correspondence: Dr D N Forman, Perinatal Epidemiological Research Unit, Department of Obstetrics and Gynecology, Asrhus University Hospital, Forteledet 16, st, DK 8240 Risskov, Denmark. Fax +45 89 49 63 73.