Evid Based Nurs 4:58 doi:10.1136/ebn.4.2.58
  • Clinical prediction guide

An antenatal index predicted postpartum depression with high sensitivity and moderate specificity

 QUESTION: Are there demographic, perinatal, and psychosocial risk factors that can be used to develop a predictive index for postpartum depression?


2 cohort studies: 1 to identify the predictors (derivation cohort) and 1 to validate their predictive ability (validation cohort).


Antenatal care clinic and delivery ward in a university hospital in Denmark.


6790 Danish speaking women (mean age 30 y) who attended an antenatal programme for a second trimester examination and who gave birth between 1 January 1994 and 31 December 1995 formed the derivation cohort. 528 women enrolled in the antenatal programme in the 4 months immediately before and after the study period formed the validation cohort.

Description of prediction guide

2 predictive indices were considered: 1 index involving only antenatal risk factors, and the other involving both antenatal and perinatal risk factors. Potential risk factors were grouped into sociodemographic characteristics, psychopathological and social status, and …

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