Evid Based Nurs 4:46 doi:10.1136/ebn.4.2.46
  • Treatment

Contamination of urine specimens from women with acute dysuria did not differ with collection technique

 QUESTION: Does contamination of urine specimens from women with acute dysuria differ with collection technique (midstream, midstream plus vaginal tampon, or no cleansing)?


Randomised {allocation not concealed}*, blinded (outcome assessors), controlled trial.


An outpatient clinic at Rutgers University, New Jersey, USA.


242 consecutive women (mean age 21 y), mostly undergraduates, with symptoms suggestive of cystitis. Exclusion criteria were antibiotic use or urethral instrumentation in the previous 7 days, or known urological abnormality or nephrolithiasis. Follow up was complete.


84 women were allocated to midstream collection and were instructed to cleanse the perineum with a bactericidal wipe by wiping from front to rear, to spread the labia, discard the first urine output, and then collect a midstream specimen in a clean, non-sterile container. 81 women were …

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