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QUESTION: When giving routine immunisations to infants, does needle length affect the incidence of local reactions?
Design
Randomised (allocation concealed), blinded (outcome assessors), controlled trial with follow up to 3 days.
Setting
8 general practices in Buckinghamshire, UK.
Participants
119 healthy infants attending routine immunisation clinics. Exclusion criteria were those applicable to children receiving primary immunisations. 92% of infants (58% boys) completed follow up.
Intervention
58 infants were allocated to receive their third dose of diphtheria, pertussis, and tetanus and Haemophilus influenzae type b vaccines (due at 16 weeks) given with a 23 gauge, 25 mm (longer) blue hub needle …
Footnotes
Source of funding: Smith and Nephew Foundation.
For correspondence: Ms L Diggle, Oxford Vaccine Group, University Department of Paediatrics, John Radcliffe Hospital, Oxford OX3 9DU, UK. Fax +44 (0)1865 221068.
A modified version of this abstract appears in Evidence-Based Medicine.