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Clinically useful measures of the effects of treatment

https://doi.org/10.1136/ebn.4.2.36

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    Footnotes

    • ↵* In this article, we use RRR to illustrate treatment effects. 2 other terms which are used to illustrate treatment effects are: relative benefit increase (RBI), defined as the proportional increase in rates of good outcomes between experimental and control participants in a trial, and relative risk increase (RRI), defined as the proportional increase in rates of bad outcomes between experimental and control participants in a trial. Both of these are calculated identically to RRR (ie, CER–EER/CER).4

    • ↵† Although we use ARR to illustrate treatment effects in this paper, 2 other terms which reflect absolute differences are absolute benefit increase (ABI), defined as the absolute arithmetic difference in rates of good outcomes between experimental and control participants in a trial, and absolute risk increase (ARI), defined as the absolute arithmetic difference in rates of bad outcomes between experimental and control participants in a trial. Both of these are calculated identically to ARR (ie, CER–EER).4