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  • A 0.5% chlorhexidine gluconate in 70% isopropyl alcohol swab was more effective than 2 other methods for intravenous skin antisepsis

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A 0.5% chlorhexidine gluconate in 70% isopropyl alcohol swab was more effective than 2 other methods for intravenous skin antisepsis

https://doi.org/10.1136/ebn.3.4.119

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    LeBlanc A, Cobbett S.Traditional practice versus evidence-based practice for IV skin preparation.Can J Infect Con2000 ;Spring:9–14

    QUESTION: Which of 3 methods for skin antisepsis before peripheral intravenous (IV) therapy is most effective for preventing catheter related infection?

    Design

    Randomised {allocation concealed}*, blinded {investigators, patients, outcome assessors}*, controlled trial with follow up at 72 hours after removal of the IV catheter.

    Setting

    A 139 bed, acute care hospital in Yarmouth, Nova Scotia, Canada.

    Patients

    300 patients who required a peripheral IV catheter and were able to read and understand English. Exclusion criteria was an IV catheter that remained in situ for <8 hours. Patients were recruited from the hospital's medical, surgical, intensive care, obstetrics and gynaecology, and outpatient and emergency services. Follow up was 81%.

    Intervention

    Before peripheral IV insertion, patients were allocated to receive 1 …

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    Footnotes

    • Sources of funding: SoluMed Inc and Johnson and Johnson.

    • For correspondence: Ms A LeBlanc, Yarmouth Regional Hospital Operated by the Western Regional Health Board, 60 Vancouver Street, Yarmouth, NS B5A 2P5, Canada. Fax +1 902 742 0369.

    • ↵* Information provided by author.

    • ↵† p Value calculated from data in article.