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Evid Based Nurs 3:89 doi:10.1136/ebn.3.3.89
  • Causation

Review: a mean alcohol intake of 30 g/day is associated with benefits for some biological markers of coronary artery disease

(1999) BMJ 319, 1523. Rimm EB, Williams P, Fosher K. , et al. . Moderate alcohol intake and lower risk of coronary heart disease: meta-analysis of effects on lipids and haemostatic factors.. Dec 11;. :. –8..


 
 QUESTION: What is the association between moderate alcohol intake and biological markers of risk of coronary artery disease (CAD)?

Data sources

Studies were identified by searching Medline (1966–98), bibliographies of review articles, and proceedings of meetings and symposia and by handsearching the Journal of the Alcohol Beverage Medical Research Foundation and Alcohol Research.

Study selection

Studies published in English were selected if participants did not have diagnosed CAD, diabetes, or alcohol dependence and if biomarkers related to the risk of CAD were assessed. Studies on lipid factors were included only if the intervention period was ≥7 days. All studies of coagulation and thrombolytic factors were included. Studies of lipid peroxidation and platelet aggregation and studies in which ≥100 g/day of ethanol were consumed were excluded.

Data extraction

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