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  • A semirecumbent body position led to a lower rate of nosocomial pneumonia than a supine position in mechanically ventilated adults

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A semirecumbent body position led to a lower rate of nosocomial pneumonia than a supine position in mechanically ventilated adults

https://doi.org/10.1136/ebn.3.3.84

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    Drakulovic MB, Torres A, Bauer TT, et al.Supine body position as a risk factor for nosocomial pneumonia in mechanically ventilated patients: a randomised trial.Lancet1999 Nov 27;354:1851–8OpenUrlCrossRefPubMedWeb of Science

    QUESTION: In patients who are intubated and mechanically ventilated, is a semirecumbent body position more effective than a supine body position for reducing the incidence of nosocomial pneumonia?

    Design

    Randomised (allocation concealed), unblinded, controlled trial with follow up for 72 hours after extubation. An interim analysis was planned.

    Setting

    2 intensive care units (ICUs) of a 1000 bed, tertiary care, university hospital in Spain.

    Patients

    90 patients (mean age 65 y, 76% men) in the ICU who had been intubated and mechanically ventilated. Exclusion criteria were recent abdominal surgery or neurosurgery, shock refractory to vasoactive drugs or volume therapy, or previous endotracheal intubation. 96% …

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    Footnotes

    • Sources of funding: Commisionat per a Universitats i Recerca de la Generalitat de Catalunya 1997 Suport dels Grups de Recerca; Fundació Clinic; Comissió Interdepartamental de Recerca i Innovació Tecnológica; IDIBAPS; and European Respiratory Society.

    • For correspondence: Dr A Torres, Hospital Clinic i Provincial, Servei de Pneumologia i Al.lèrgia Respiratoria, Villarroel, 170, E-08036 Barcelona, Spain. Fax +34 93 227 5454.

    • A modified version of this abstract appears in ACP Journal Club.