A semirecumbent body position led to a lower rate of nosocomial pneumonia than a supine position in mechanically ventilated adults
QUESTION: In patients who are intubated and mechanically ventilated, is a semirecumbent body position more effective than a supine body position for reducing the incidence of nosocomial pneumonia?
Randomised (allocation concealed), unblinded, controlled trial with follow up for 72 hours after extubation. An interim analysis was planned.
2 intensive care units (ICUs) of a 1000 bed, tertiary care, university hospital in Spain.
90 patients (mean age 65 y, 76% men) in the ICU who had been intubated and mechanically ventilated. Exclusion criteria were recent abdominal surgery or neurosurgery, shock refractory to vasoactive drugs or volume therapy, or previous endotracheal intubation. 96% of patients completed the trial.
43 patients were allocated to a semirecumbent body position (45° from the horizontal) and 47 to a supine body position. Patients …