Evid Based Nurs 3:78 doi:10.1136/ebn.3.3.78
  • Treatment

Review: antibiotics for sore throat reduce symptoms at day 3 and the incidence of rheumatic fever and otitis media

 QUESTION: In primary care settings, are antibiotics effective for adults and children with acute sore throats?

Data sources

Studies were identified by searching Medline with the terms pharyngitis, sore throat, and tonsillitis; the Cochrane Library; the Cochrane Acute Respiratory Infections Group trials register; and bibliographies of included studies. Inclusion dates of the studies were 1945–99.

Study selection

Controlled trials were selected if they compared antibiotics with placebo, if the patients had symptoms of acute sore throat and were in primary care settings, and if outcomes included incidence of acute rheumatic fever within 2 months, acute glomerulonephritis within 1 month, acute otitis media, acute sinusitis, quinsy (peritonsillar abscess), or symptoms of throat soreness, headache, or fever.

Data extraction

Data were extracted or sought from the authors of trials on study quality, publication date, patient characteristics, antibiotics including duration, outcomes, symptom resolution, and adverse effects.

Main results

22 …

Free Sample

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of EBN.
View free sample issue >>

EBN Journal Chat

The EBN Journal Chat offers readers the opportunity to participate in discussion about research articles and commentaries from Evidence Based Nursing (EBN).

How to participate >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Navigate This Article