Evid Based Nurs 3:50 doi:10.1136/ebn.3.2.50
  • Treatment

Review: allylamines, azoles, undecenoic acid, and tolnaftate are effective for fungal skin infections of the foot

Comparison of topical treatment regimens for failure to cure fungal skin infections of the foot at 1–8 weeks of follow up*

Comparison regimens (weighted event rates) Number of studies RRR (95% CI) NNT (CI)
*Abbreviations defined in glossary; RRR, NNT, and CI calculated from data provided by the author.
Allylamines (23%) v placebo (80%) 12 65% (56 to 72) 2 (2 to 3)
Azoles (23%) v placebo (61%) 17 68% (56 to 76) 3 (3 to 4)
Undecenoic acid (29%) v placebo (75%) 4 61% (44 to 72) 3 (2 to 4)
Tolnaftate (52%)v placebo (70%) 3 26% (4 to 43) 6 (4 to 31)

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