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Evid Based Nurs 3:49 doi:10.1136/ebn.3.2.49
  • Treatment

Review: penicillin V is better than placebo and equal to non-penicillins for acute maxillary sinusitis

Antibiotics v placebo or other antibiotics for acute maxillary sinusitis*

Outcomes Comparison (no. of RCTs) Weighted event rates RBI (95% CI) NNT (CI)
Clinical cure rate Penicillin v control (2) 35% v 19% 72% (0 to 196) 7 (4 to 39)
RRR (CI)
*RCTs=randomised controlled trials. Other abbreviations defined in glossary; RRR, RBI, NNT, and CI calculated from data in article.
Dropouts from adverse events Macrolide/ cephalosporin v amoxicillin- clavulanate (9) 2% v 4% 56% (22 to 75) 44 (25 to 200)

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