Evid Based Nurs 3:42 doi:10.1136/ebn.3.2.42
  • Treatment

Compared with dimethicone, 2 weeks of spinal manipulation reduced infantile colic behaviour at 4–11 days after initial treatment

 QUESTION: Does spinal manipulation reduce infantile colic behaviours in the short term compared with dimethicone?


Randomised (concealed), blinded (outcome assessor), controlled trial with follow up to 11 days.


A suburb of Copenhagen, Denmark.


Health visitor nurses recruited 50 consecutive infants who were 2–10 weeks of age, and had ≥1 violent spells of crying (≥3 h each day) for ≥5 of the 7 previous days; typical colic behaviour during crying spells (ie, motor unrest, flexing knees against abdomen, and extending trunk, neck, and extremities) and not (or only temporarily) comforted by nappy changes, dummies, or being picked up, walked, or cradled; no known diseases or symptoms of diseases other than infantile colic; and average weight gain ≥150 grams per week. Follow up at day 11 was 80%.


25 infants were allocated to 2 weeks (approximately …

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