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  • In newborns, changing parenteral nutrition sets every 48 hours rather than every 24 hours did not increase infusate contamination

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In newborns, changing parenteral nutrition sets every 48 hours rather than every 24 hours did not increase infusate contamination

https://doi.org/10.1136/ebn.3.1.9

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    Fox M, Molesky M, Van Aerde JE, et al.Changing parenteral nutrition administration sets every 24 h versus every 48 h in newborn infants.Can J Gastroenterol1999 Mar;13:147–51OpenUrlPubMedWeb of Science

    QUESTION: In newborn infants, does changing total parenteral nutrition fluid administration sets (TASs) every 48 hours, rather than every 24 hours, increase the rate of contamination of infusates (amino acid plus dextrose solution [AADS] or lipid emulsion)?

    Design

    Randomised (allocation not concealed), blinded (unclear), controlled trial.

    Setting

    A neonatal intensive care unit in Edmonton, Alberta, Canada.

    Patients

    166 infants who received total parenteral nutrition during a 12 month period. Infusate samples from 148 infants (89%) (mean gestational age 32.8 wks, mean birth weight 2036 g, mean postnatal age 12.9 d) were included in the analysis.

    Intervention

    53 infants were allocated to have their TAS changed every 24 hours. 113 infants were allocated to have their TAS changed every 48 hours. The TAS was …

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