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Systematic review with meta-analysis
Pregnancy in women with sickle cell disease is associated with risk of maternal and perinatal mortality and severe morbidity
  1. Eugene Oteng-Ntim
  1. Guy's and St Thomas' Hospital, London, UK
  1. Correspondence to : Dr Eugene Oteng-Ntim, Women's Health Services, 10th Floor, North Wing, Guy's and St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, UK; eugene.oteng-ntim{at}gstt.nhs.uk

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Implication for practice

  • Pregnancy in patients with sickle cell disease (SCD) is associated with the risk of maternal and perinatal mortality and severe morbidity.

  • Findings provide important estimates on associated mortality and morbidity for policymakers, clinicians and researchers to work together to improve on these adverse outcomes.

  • There is a need for multidisciplinary care in order to manage the multisystem nature of complications associated with SCD in pregnancy.

Context

Sickle cell disease (SCD) is among the most common genetic conditions globally.1 SCD has a significant worldwide public …

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